UNLV Study: Aerobic Exercise Key to Slowing Parkinson’s Progression

LAS VEGAS, NV — Researchers at the UNLV School of Integrated Health Sciences released findings yesterday, April 30, confirming that regular aerobic exercise is one of the most effective non-pharmacological treatments to slow the progression of Parkinson’s disease.

The Science of “Brain Fertilizer”

Inflammation Reduction: The study, led by interim dean and physical therapist Merrill Landers, suggests that aerobic activity directly reduces the brain inflammation at the root of the disease.
The BDNF Factor: Exercise triggers an increase in brain-derived neurotrophic factor (BDNF), a protein Landers describes as “fertilizer for the brain” because it promotes the growth and survival of neurons.
Anti-Inflammatory Signals: BDNF also signals muscles and tissues to release anti-inflammatory markers throughout the body during activity.

Finding the “Sweet Spot”

To maximize these neuroprotective benefits, researchers recommend a specific intensity for Parkinson’s patients:

Intensity Zone: Optimal BDNF production occurs at 60%–75% of maximum heart rate—an intensity where the patient can speak in short sentences but not easily hold a full conversation.
Sustainable Modalities: Recommended activities include treadmill walking, cycling, and dancing, provided they are sustained long enough to trigger the protein boost.
Comprehensive Care: Experts noted that while aerobic exercise is a “core component,” it should be part of a well-rounded regimen including strength and balance training.